Emergency teams are investigating whether anybody was inside a vehicle which plunged off cliffs on the Isle of Wight.
The vehicle ended up in water after falling from Culver Cliffs but the tide and weather conditions were hampering efforts to retrieve it.
A Hampshire Constabulary spokeswoman said: "It appears that a vehicle has gone over the cliff and is in the water.
"Due to the incoming tide and current weather conditions, and in consultation with the coastguard, it's not currently possible to retrieve this vehicle. It's not known if anyone is in the vehicle at this time."
A police spokesman said officers were concerned for the wellbeing of a 20-year-old man who left his home in Newport in the early hours driving a van.
A member of the public alerted police at 2.52am raising concerns about the man and a short time later they received a call reporting that a vehicle had gone over the cliffs at Culver.
The spokesman said: "Due to the incoming tide and current weather conditions, it is not currently possible to retrieve the vehicle. A vessel from Hampshire Constabulary's Marine Unit is en-route to the coast off Culver to assess the state of the vehicle, confirm its identity, and whether anyone is in the vehicle.
"A 20-year-old man from Newport on the Isle of Wight remains missing at this time. Officers are in contact with the man's family. There is no evidence to suggest suspicious circumstances or a crime at this time, but police must keep an open mind until the vehicle is assessed and recovered."
Paul Charles, 53, and his wife Jacqueline, 48, were killed when they drove off the same cliff in their Renault Scenic car in August last year.
An inquest heard the pair had a "destructive relationship" and the coroner recorded verdicts of suicide.