Stuart Broad took two wickets on the third morning of the third Investec Test as England began their long haul to try to bowl India out twice at the Ageas Bowl.
The tourists, replying to 569 for seven declared, were 108 for three at lunch.
Alastair Cook preferred Chris Woakes to Broad initially, in tandem with James Anderson.
Broad, perhaps feeling a small point to prove, struck in his second over when he got a short ball to follow Cheteshwar Pujara and take the glove as the batsman tried to leave but instead gave England's new wicketkeeper Jos Buttler his first catch in Test cricket.
Murali Vijay had been runless for 20 deliveries on the resumption, Pujara scoring the first 20 runs of a sunny morning.
It was Vijay who inadvertently gave England a potential problem with an edge off Anderson just short of Ian Bell at second slip, resulting in an awkward blow to the left thumb which forced the fielder - and key batsman - off the pitch and to hospital for an X-ray.
However, the results revealed no broken bones as the England and Wales Cricket Board tweeted: "No fracture, acute bruising, so he'll remain off the field for treatment."
Chris Jordan replaced Anderson but could not find his range from the northern end - so it was just as well for England that Broad was in the middle of a particularly testing spell, and one which proved too much for Vijay.
He had just beaten the opener on the outside as he pushed away from his body when, next ball, Vijay remained uncertain against a tight line and this time paid for it with an inside-edge down on to his stumps.
With Jordan still misfiring, Cook turned early to Moeen Ali - a move which should have brought another wicket, when Ajinkya Rahane gloved the off-spinner down the leg-side on eight only for umpire Rod Tucker to decide not out after Buttler took his second 'catch'.